Visual Impairment in Alzheimers Disease :: Opthamology Alzheimers Disease Essays

Visual equipment casualty in Alzheimers DiseaseThe documentation of a severe form of insanity by Alois Alzheimer in 1907 began a massive investigation of the cause of this disorder. round of the common symptoms of Alzheimers Disease consist of memory loss, damage language ability, stricken judgement, and learning (M. Wong, et al. , 1997). Alzheimers Disease (AD) is mainly a disease of the cerebral cortex. Alzheimers is pronounced structurally by the senile plaques, neurofibrillary tangles, and severe loss of neurons and synapses in the cerebral cortex. Alzheimers is a neurodegenerative disorder ( Hof, Vogt, Bouras, and Morrison 1997). Recent attention has been focused on optic dysfunction in Alzheimers Disease (K. U. Loffler, D. P. Edward, & M. O. M. Tso 1995). Visual ProblemsDuring the clinical evaluation of patients with nuts to moderate dementia of the AD type, visual difficulties such as topographical agnosia, visual agnosia, alexia without agraphia, and prosopagnosia ar e detected. AD patients have The problem of describing the mortal components of a picture is consistent with the severity of cytochrome oxidase (C.O.) deficits in the association cortical areas. Other deficits experienced by AD patients were texture discrimination, blue-violet discrimination, and 4.72 deg/sec inquiry detection. When AD patients were compared to other age-matched controls, AD patients had shown specific deficits in contrast sensitivity. Deficits in color vision were only age-related (M. Wong-Riley, et al. , 1997). StudiesSelective degeneration of large ganglion jail cell axons was observed in the optic nerves of AD patients, which suggested an baulk of broad-band origin visual function. Although studies show that the broad-band visual capabilities are not selectively impaired in AD. Dorsal LGN studies have shown that both the magno- and parvicellular neurons were greatly touch in AD patients. Strangely, AD patients were impaired at low frequencies instead of th e mettlesome frequencies, like in old age. This implies that regions controlling the low spacial absolute frequency processing in the primary visual cortex would be affected more than those for high frequency processing (M. Wong-Riley, et al. , 1997). The neuropathologic examination of the brains with visual impairment in the Hof et al. (1997) study revealed cortical atrophy dominating on the scum bag parietal cortex and occipital lobe(Hof et al.). A study by Beta-amyloid is considered an weighty factor in AD and was shown to be the major cause in senile plaques. AcetylcholineA number of neurotransmitters and neuromodulators, including acetylcholine (ACh), somatostatin and glutamate have been found to be substandard in Alzheimers disease (AD).